![]() Most of us consume caffeine in safe amounts, as coffee, tea or chocolate but just a small amount of anhydrous caffeine powder can be lethal. While few cases of accidental ingestion of caffeine by dogs have been described, the intentional use of a concentrated caffeine source to cause mortality in a dog has not been previously reported. Caffeine powder caused the accidental death of a 23-year old man in Britain. A suggested treatment regimen for caffeine intoxication in dogs is described. Based on the history, clinical signs, and the detection of caffeine in the gastric contents and meat, a presumptive diagnosis of malicious caffeine poisoning was made. Other potential caffeine sources include guarana, brewed and concentrated coffee, and caffeine-containing beverages. Although no tablet remnants were observed in the bait, tablets could have been crushed and/or dissolved. Acute intoxication affects the cardiovascular, pulmonary, neurologic, gastrointestinal, and metabolic systems. By conservative estimates, the dog would need to ingest approximately 500-550 g of the meat to reach the MLD(50). A commercially available 200-mg tablet formulation of caffeine was considered to be a possible source but this was not confirmed. Caffeine is a methylxanthine alkaloid with a reported canine oral median lethal dose (MLD(50)) of 140 mg/kg (range 120-200 mg/kg). Caffeine concentration in the ground meat was estimated at 1 %. Caffeine content absolutely has a lot to do with how the beans are roasted, and very very little to do with brew method unless you are significantly under-extracting your beans. Analysis of gastric contents by gas chromatography-mass spectrometry confirmed the presence of caffeine. Death wish coffee caffeine content is normally around 650-900 milligrams of caffeine per cup. Approximately 11 h postexposure the dog died.Īmong tissues submitted for toxicological analysis, urine was negative for EG, ground meat was negative for certain drugs of abuse, and gastric contents were negative for zinc/aluminum phosphide and metaldehyde. When presented to a veterinary clinic, plasma ethylene glycol (EG) testing was positive, and the dog was given ethanol and lactated Ringer's solution intravenously. A 4-year-old, 37 kg, male German shepherd developed hyperthermia, tachycardia, and agitation following consumption of ground meat found in the backyard of its owner.
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